Argentina coach Edgardo Bauza has confirmed Lionel Messi is unavailable for Tuesday's World Cup qualifying match against Venezuela after suffering an injury setback.
The Barcelona maestro made his Albiceleste comeback in Thursday's game, having announced his international retirement following the Copa America Centenario.
The 29-year-old scored the only goal of the game as Argentina recorded a 1-0 victory over Uruguay, but gave the coaching staff and medical team cause for concern after the full-time whistle after complaining of some pain in his groin.
And, after having his injury assessed, Messi will be rested for the upcoming clash with Venezuela as a precaution.
"Messi won't be able to play in the next match; there is inflammation in that groin injury and we must rest him," Bauza told reporters.
A statement from the Argentina Football Association further clarified the player's injury status.
"The captain of the national team is suffering from inguinocrural pain. As a result, he will not participate in the next World Cup qualifying match," the statement read.
"This morning, Lionel Messi underwent medical and kinesiological treatment for the groin and thigh pain.
"It is recommended that he continue to rest from activity and will not play against Venezuela."