Crystal Palace welcome Stoke to the capital in an all-Premier League encounter on Saturday with a place in the fifth round of the FA Cup up for grabs.
The Eagles booked their spot in the fourth round by seeing off another top-flight rival in Southampton but they are in a slump at the moment, having lost all four their league games in 2016.
Indeed Alan Pardew's team have not tasted success since beating the Potters 2-1 at the Britannia Stadium on December 19, their winless run in the league stretching to six outings with the 3-1 loss to Tottenham last weekend.
The Staffordshire outfit were given an easier draw in the third round after being paired with League One side Doncaster, who made their Premier League opponents work for their narrow 2-1 win.
Mark Hughes' men have had a busy January, which ultimately ended in disappointment following a penalty shootout defeat to Liverpool in the Capital One Cup semi-finals.
The Potters are searching for their first victory in four games, having lost 3-0 at Leicester last weekend, although they did manage to hold Arsenal to a goalless draw the weekend before.
In team news, new Palace signing Emmanuel Adebayor is available to make his debut, but will not start as he is not fully match fit.
Pardew must also do without midfielder Bakary Sako and winger Yannick Bolasie as the pair continue their recovery from hamstring and knee injuries respectively.
Visiting boss Hughes also has a few injuries to contend with, the latest casualty being Charlie Adam.
The midfielder limped off with a torn calf muscle shortly after his introduction from the bench against the Reds in midweek and faces up to six months on the sidelines.
Adam joins defenders Ryan Shawcross (back) and Geoff Cameron (ankle) on the treatment table, while striker Marko Arnautovic could be rested after taking a knock in Tuesday's cup-tie.