John Isner has chosen to defend his BB&T Atlanta Open title rather than compete in the Rio Olympic Games.
The American revealed he will remain in the US in search of a record fourth Atlanta Open win, rather than represent his country in Rio.
Ranked 16th in the world, Isner is highest ranked American and would be a shoo-in for the Olympic team
"It's a decision I didn't take lightly," the 30-year-old told AAP.
"Logistically, it would be pretty much impossible for me to do both."
The ten-time ATP winner competed at the 2012 event in London, losing to eventual silver medallist Roger Federer in the quarter-finals.
Isner is the second high-profile player on the ATP Tour – after Austrian number one Dominic Thiem – to reveal he is not interested in the global showpiece.