Struggling Sunderland welcome Tottenham to the Stadium of Light on Sunday looking to pick up their first win of the new Premier League campaign.
The Black Cats are favourites to be relegated this campaign having picked up only two points in their first four Premier League matches and suffering heavy defeats to Leicester and newcomers Norwich.
Italian striker Fabio Borini is expected to make his debut after re-signing for the North East outfit from Liverpool but fellow attackers Adam Johnson and Jordi Gomez both remain sidelined despite returning to training earlier this week.
Another who won't be involved for Dick Advocaat's side is American loanee DeAndre Yedlin from Spurs, who is ineligible to face his former club and is yet to make his Black Cats debut.
Spurs, meanwhile, head to the north east also without a victory so far this campaign having managed three draws from their last three games following their opening day defeat to Manchester United.
Off-season signing Son Heung-min will likely be involved at some stage after joining Spurs from Bayer Leverkusen and may in fact start the clash in place of Christian Eriksen, who has a knee problem.
Moussa Dembele is also sidelined with a foot problem and Mauricio Pochettino recently revealed that the game may come too soon for new-singing Clinton N'Jie, who is short of match fitness.