Manchester United and Liverpool will both be looking for their first big performance of the season when they meet at Old Trafford on Saturday.
The two Premier League giants have had very similar results in the opening round of fixtures.
Both started out with 1-0 victories in their first couple of games and were then held to a 0-0 draw on matchday three before slumping to defeats ahead of the international break.
For United, wins over Tottenham and Aston Villa preceded a draw with Newcastle and defeat to Swansea, but they will take confidence from having done the double over the Reds last season, including a 3-0 win the corresponding fixture.
For the Merseysiders, that goalless stalemate came against Arsenal after claiming wins over Stoke and Bournemouth. But a 3-0 thrashing at home to West Ham will have left a sour taste in the mouths of the players as they headed out for international duty.
United boss Louis van Gaal probably won't be able to call on veteran midfielder Michael Carrick (calf/shin), while defender Phil Jones is also expected to miss out through illness.
Liverpool manager Brendan Rodgers has a trio of injury doubts, with Adam Lallana (thigh), Jordan Henderson (ankle) and Joe Allen (hamstring) all rated as very doubtful.
Playmaker Philippe Coutinho is certain to miss out through suspension after his red card against the Hammers, while striker Daniel Sturridge is yet to make his return.