Lions head coach Johan Ackermann has made four changes to his starting XV for Saturday's clash with the Blues in Johannesburg.
In the forwards, tighthead prop Julian Redelinghuys and hooker Malcom Marx return to the starting line-up which means the Lions will start with their first-choice front row.
Both have been out due to injuries and replace Armand van der Merwe and Pieter Scholtz respectively. Meanwhile, Andries Ferreira, who started in the Lions' previous match against the Hurricanes in Round 10, is bracketed at lock with Martin Muller.
In the back-line, Ross Cronjé gets the nod at scrum-half with Faf de Klerk dropping to the bench. He forms the halfback combination with Elton Jantjies, who passed a fitness test on Thursday.
Rohan Janse van Rensburg comes in to partner Lionel Mapoe in midfield with Howard Mnisi moving to the bench.
A new face among the reserves is new recruit Sylvian Mahuza who has been in action for the Golden Lions XV in the Currie Cup qualifying competition.
Lions: 15 Jaco Van Der Walt, 14 Ruan Combrinck, 13 Lionel Mapoe, 12 Rohan Janse Van Rensburg, 11 Courtnall Skosan, 10 Elton Jantjies, 9 Ross Cronje, 8 Warren Whiteley (c), 7 Warwick Tecklenburg, 6 Jaco Kriel, 5 Franco Mostert, 4 Martin Muller/Andries Ferreira, 3 Julian Redelinghuys, 2 Malcolm Marx, 1 Dylan Smith
Replacements: 16 Armand Van Der Merwe, 17 Corne Fourie, 18 Jacques Van Rooyen, 19 Ruan Ackermann, 20 Cyle Brink, 21 Faf De Klerk, 22 Howard Mnisi, 23 Sylvian Mahuza
Date: Saturday, May 14
Venue: Emirates Airlines Stadium, Johannesburg
Kick-off: 19:15 local (17:15 GMT)
Referee: Jaco van Heerden
Assistant Referees: Jaco Peyper, Pro Legoete
TMO: Shaun Veldsman