However, fellow midfielders Leon Osman (groin) and James McCarthy (ankle) both returned to training on Friday and should be available.
Striker Romelu Lukaku reported no after-effects from his first appearance in a month last weekend.
Manchester United right-back Rafael will miss the rest of the season with a rib injury, and joins a growing list of absentees for Louis van Gaal’s men.
Phil Jones (ankle), Michael Carrick (calf) and Marcos Rojo (adductor) all missed last weekend’s defeat to Chelsea and are not fit to feature.
Daley Blind and Adnan Januzaj appear to be available after both overcoming ankle injuries, while Jonny Evans returns after completing his six-game ban.