The Reds will play in Kuala Lumpur on July 24 against a Malaysian XI at the Bukit Jalil National Stadium.
The Football Association of Malaysia (FAM) are organising the event.
LFC CEO Ian Ayre says: "We visited Kuala Lumpur as part of our 2011 pre-season tour and the support we received was incredible, not only from the 80,000 fans that turned out to watch us play at Bukit Jalil, but all our fans in Malaysia throughout our visit.
"Pre-season is an important time for the team as they prepare for the upcoming season and the match against the Malaysian XI is an exciting part of that preparation. The tour gives our supporters a chance to see the team up close, no matter how far away from Anfield they might live."
The FAM general-secretary Dato' Hamidin Haji Mohd Amin said: "The national football governing body is truly honoured to host Liverpool once again and are excited by the upcoming fixture.
"It's not that we often get to see English Premier League stars. We watch them in awe in our television sets as they take on their opponents, mesmerising them with their gifted football skills.
"Watching our Malaysian XI play Liverpool is going to be an enthralling experience for all fans."